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KMID : 0375219940090010053
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Journal of Il Sin Christian Hospital
1994 Volume.9 No. 1 p.53 ~ p.64
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Study of Biochemical Markers of Bone Turnover
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Abstract
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We studied the biochemical markers of bone turnover in 202 healthy postmenopausal women.
We checked fasting serum Ca. P, Osteocalcin, total Alkaline Phosphatase, urine Ca/Cr 100mg & bone Mineral Density(L2-4) by DEXA.
Among these markers, serum total Alk. P. is most sensitive marker of bone turnover because it is negatively correlated with BMD c r=-0.288.
Serum osteocalcin is next sensitive marker of bone turnover because it is negatively correlated c BMD c r=-0.259.
Fasting urine Ca/Cr is a poor marker(r=-0.032).
I think we must check more sensitive bone resorption marker ex. Urinary pyridioline, deoxypyridinoline for understanding of bone metabolism & follow up of osteoporosis.
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